Dear Sara<div><br></div><div>Not an expert of Heme but I think one problem could be the multiplicity (and charge?) of your system</div><div>Fe2+ in an aqueous solution should be high spin (Multiplicity 5)</div><div><div><a href="https://doi.org/10.1021/acs.jpclett.2c00380">https://doi.org/10.1021/acs.jpclett.2c00380</a><br></div><br></div><div>In your input</div><div><br></div><div> BASIS_SET_FILE_NAME BASIS_MOLOPT<br> POTENTIAL_FILE_NAME GTH_POTENTIALS<br> <b> MULTIPLICITY 1<br> CHARGE -2</b><br></div><div><b><br></b></div><div>Check also for HEME</div><div><br></div><div><a href="https://doi.org/10.1021/acs.inorgchem.6b01360">https://doi.org/10.1021/acs.inorgchem.6b01360</a><br></div><div><br></div><div>Hope it helps</div><div><br></div><div>Best</div><div>Ivan</div><div class="gmail_quote"><div dir="auto" class="gmail_attr">On Tuesday, September 13, 2022 at 5:00:25 PM UTC+3 salla...@gmail.com wrote:<br/></div><blockquote class="gmail_quote" style="margin: 0 0 0 0.8ex; border-left: 1px solid rgb(204, 204, 204); padding-left: 1ex;">Dear all, <div><br></div><div>I am having problems on a geometry optimisation of a heme group with Fe2+ using PBE in CP2K. My calculations run and the total energy is decreasing. However, the job has been running for almost a month and it doesn't seem to converge. </div><div><br></div><div>I am not an expert on CP2K nor on transition metals. I would really appreciate it if you could help me sort this out. I have attached the restart file and the output for clarity. </div><div><br></div><div>Thanks a lot, </div><div><br></div><div><br></div><div>Sara</div></blockquote></div>
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