<html><body><div style="color:#000; background-color:#fff; font-family:ÐÂËÎÌå, nsimsun, sans-serif;font-size:13pt"><div><span>Dear </span>Sandeep,</div><div>Thanks for your reply. Actually, I want to use the <br></div><div> Thermodynamic integration, and I have no experience <br></div><div>on this method. Could give me some advice?</div><div><br></div><div>Look forward to your reply.</div><div>Best regards,</div><div>Ross,sun</div><br></div></body></html>