Thanks a lot for all your comments.<br><br>Marius<br><br><div class="gmail_quote">On Wed, Mar 18, 2009 at 5:14 PM, Teodoro Laino <span dir="ltr"><<a href="mailto:teodor...@gmail.com">teodor...@gmail.com</a>></span> wrote:<br>
<blockquote class="gmail_quote" style="border-left: 1px solid rgb(204, 204, 204); margin: 0pt 0pt 0pt 0.8ex; padding-left: 1ex;"><br>
The bug (which was depending on the way of reading natively AMBER prmtop<br>
files) is now fixed in the CVS (thanks for reporting)!<br>
Just few comments about your QMMM setup.<br>
1) The way it is setup you will hardly have a conserved energy (you have<br>
a PERIODIC MM) but you don't use the periodic QMMM version (see PERIODIC<br>
in QMMM). Alternatively you may think about using a spherical cutoff for<br>
the electrostatic (that is tapering the interaction after a certain cutoff).<br>
2) you may want to specify proper covalent radius for the QMMM<br>
electrostatic interactions (at the moment you rely on the default which<br>
is 0.78 (if I'm not wrong) for all atoms).<br>
<br>
Have a nice QMMM.<br>
Teo<br>
<br>
p.s.: about the xc_deriv and xc_smooth_rho I would not suggest you to<br>
use them unless you really know what you are doing. Most of the time you<br>
don't need to specify those keywords (only for few pathological cases.<br>
CH4 or H2O are definitely not one of them).<br>
<div><div></div><div class="h5"><br>
<br>
Marius Retegan wrote:<br>
> Hi,<br>
><br>
> In my continuing saga of using cp2k for running qm/mm calculations I<br>
> have encounter yet another bump.<br>
> While using the input below I get this error "FORCEFIELD| Missing Bond<br>
> ( CT, HC)" and angle ...<br>
><br>
> &GLOBAL<br>
> PROJECT mebox_qmmm<br>
> RUN_TYPE MD<br>
> PRINT_LEVEL LOW<br>
> &END GLOBAL<br>
><br>
> &MOTION<br>
> &MD<br>
> ENSEMBLE NVT<br>
> STEPS 1000<br>
> TIMESTEP 1.0<br>
> TEMPERATURE 298<br>
> &THERMOSTAT<br>
> REGION GLOBAL<br>
> TYPE CSVR<br>
> &CSVR<br>
> TIMECON 100<br>
> &END CSVR<br>
> &END THERMOSTAT<br>
> &END MD<br>
> &PRINT<br>
> &RESTART OFF<br>
> &END RESTART<br>
> &RESTART_HISTORY OFF<br>
> &END RESTART_HISTORY<br>
> &END PRINT<br>
> &END MOTION<br>
><br>
> &FORCE_EVAL<br>
> METHOD QMMM<br>
><br>
> &DFT<br>
> CHARGE 0<br>
> BASIS_SET_FILE_NAME GTH_BASIS_SETS<br>
> POTENTIAL_FILE_NAME GTH_POTENTIALS<br>
> &MGRID<br>
> CUTOFF 280<br>
> COMMENSURATE<br>
> &END MGRID<br>
> &SCF<br>
> MAX_SCF 20<br>
> EPS_SCF 1.0E-6<br>
> &OT T<br>
> PRECONDITIONER FULL_ALL<br>
> MINIMIZER DIIS<br>
> &END OT<br>
> &PRINT<br>
> &RESTART OFF<br>
> &END RESTART<br>
> &RESTART_HISTORY OFF<br>
> &END RESTART_HISTORY<br>
> &END PRINT<br>
> &END SCF<br>
> &QS<br>
> EPS_DEFAULT 1.0E-12<br>
> MAP_CONSISTENT<br>
> EXTRAPOLATION ASPC<br>
> EXTRAPOLATION_ORDER 3<br>
> &END QS<br>
> &XC<br>
> &XC_GRID<br>
> XC_SMOOTH_RHO NN10<br>
> XC_DERIV NN10_SMOOTH<br>
> &END XC_GRID<br>
> &XC_FUNCTIONAL BLYP<br>
> &END XC_FUNCTIONAL<br>
> &END XC<br>
> &POISSON<br>
> POISSON_SOLVER MULTIPOLE<br>
> PERIODIC NONE<br>
> &END POISSON<br>
> &END DFT<br>
><br>
> &MM<br>
> &FORCEFIELD<br>
> VDW_SCALE14 0.5<br>
> EI_SCALE14 0.8333333<br>
> SCALE_CUTOFF .FALSE.<br>
> PARM_FILE_NAME mebox.prmtop<br>
> PARMTYPE AMBER<br>
> &SPLINE<br>
> EMAX_SPLINE 1.0<br>
> RCUT_NB 10<br>
> &END<br>
> &END FORCEFIELD<br>
> &POISSON<br>
> &EWALD<br>
> EWALD_TYPE SPME<br>
> ALPHA .36<br>
> GMAX 23 23 23<br>
> &END EWALD<br>
> &END POISSON<br>
> &END MM<br>
><br>
> &QMMM<br>
> E_COUPL GAUSS<br>
> USE_GEEP_LIB 7<br>
> &CELL<br>
> ABC 8.0 8.0 8.0<br>
> PERIODIC NONE<br>
> &END CELL<br>
> &QM_KIND C<br>
> MM_INDEX 1<br>
> &END QM_KIND<br>
> &QM_KIND H<br>
> MM_INDEX 2 3 4 5<br>
> &END QM_KIND<br>
> &END QMMM<br>
><br>
> &SUBSYS<br>
> &CELL<br>
> ABC [angstrom] 23.2782522 22.7141099 23.2326917<br>
> PERIODIC XYZ<br>
> &END CELL<br>
> &TOPOLOGY<br>
> COORDINATE PDB<br>
> COORD_FILE_NAME mebox_npt.pdb<br>
> CONNECTIVITY AMBER<br>
> CONN_FILE_NAME mebox.prmtop<br>
> &END<br>
> &KIND C<br>
> BASIS_SET DZVP-GTH<br>
> POTENTIAL GTH-BLYP-q4<br>
> &END KIND<br>
> &KIND H<br>
> BASIS_SET DZVP-GTH<br>
> POTENTIAL GTH-BLYP-q1<br>
> &END KIND<br>
> &END SUBSYS<br>
> &END FORCE_EVAL<br>
><br>
> If I change QMMM with FIST the input runs.<br>
><br>
> I also have some additional questions, but on somewhat different matters.<br>
><br>
> In the latest papers that I could find that use cp2k to do qm/mm<br>
> calculations (<a href="http://dx.doi.org/10.1021/ja076081h" target="_blank">http://dx.doi.org/10.1021/ja076081h</a> and<br>
> <a href="http://dx.doi.org/10.1021/jp074858n" target="_blank">http://dx.doi.org/10.1021/jp074858n</a>) the authors used a integration<br>
> step of 0.5 and 0.48. Unfortunately, they did not discussed their<br>
> choice. I'm used to running qm/mm md with other packages, but I've<br>
> always used an integration step of 1 fs. Is cp2k different :-)?<br>
><br>
> Is there any place where I can find information regarding the<br>
> parameters xc_deriv and xc_smooth_rho and are "good" choices?<br>
><br>
> Thanks,<br>
> Marius<br>
><br>
><br>
><br>
><br>
><br>
><br>
><br>
><br>
> ><br>
<br>
<br>
</div></div><div><div></div><div class="h5"><br>
</div></div></blockquote></div><br>